| Data | Casa | Visitante | Resultado |
|---|---|---|---|
| 22-10-26 15:30 | Kairat Almaty | Panathinaikos Atenas | 1:5 |
| 22-10-26 17:45 | FC Nordsjaeland | CSKA Sofia | 2:2 |
| 22-10-26 17:45 | FK Jablonec | Brighton and Hove Albion | 0:0 |
| 22-10-26 17:45 | FC Getafe | FC Lugano | 2:5 |
| 22-10-26 17:45 | Trabzonspor | Heart of Midlothian | 2:0 |
| 22-10-26 17:45 | Estrela Vermelha Belgrado | FC Copenhaga | 2:2 |
| 22-10-26 17:45 | FC Iberia 1999 | Mjaellby AIF | 1:1 |
| 22-10-26 17:45 | FK Kauno Zalgiris | Brann Bergen | 1:4 |
| 22-10-26 17:45 | Inter Escaldes | Universitatea Craiova | 1:3 |
| 22-10-26 17:45 | Pafos FC | Riga FC | 1:1 |
| 22-10-26 20:00 | Lincoln Red Imps FC | FC Twente Enschede | 1:4 |
| 22-10-26 20:00 | FK Borac | Kuopion PS | 2:0 |
| 22-10-26 20:00 | FC Midtjylland | Sint-Truidense VV | 0:1 |
| 22-10-26 20:00 | AS Mónaco | SC Friburgo | 3:0 |
| 22-10-26 20:00 | Ajax Amsterdão | Atalanta Bergamo | 2:0 |
| 22-10-26 20:00 | Sporting Braga | KAA Gent | 2:0 |
| 22-10-26 20:00 | Aarhus GF | KF Egnatia | 1:1 |
| 22-10-26 20:00 | FC Thun | HNK Hajduk Split | 0:1 |